What is NACE®?

Human beings have 23 pairs of chromosomes, a total of 46 (two copies for each pair). The first 22 pairs are numbered 1 to 22. The last pair determines the gender. Girls have two X chromosomes and boys have an X chromosome and a Y chromosome. When a chromosome is missing or there is an extra one health and developmental problems appear. When there is an extra copy of a chromosome, in other words, three copies instead of two, it is referred to as trisomy.


What is NACE?

  • NACE is a non-invasive prenatal screening test that analyzes the most frequent chromosomal alterations without compromising the pregnancy.
  • NACE is a complete prenatal test to detect anomalies in chromosomes 21, 18, and 13 (Down’s, Edward’s, and Patau’s syndromes). It also detects the most common anomalies in the sexual chromosomes (X and Y)*.
  • A simple peripheral blood extraction from the mother allows free DNA circulating in the maternal plasma to be detected via next generation sequencing technology and advanced bioinformatic analysis.
  • NACE avoids delays in the delivery time for the results. The number of cases which require a second blood extraction is less than 0.1%.